Initial Rate of an Enzyme Reaction with Noncompetitive Inhibition

Use the steady-state approximation and the equilibrium constant
KI = [E][I]/[EI] = [X][I]/[XI] to show that the initial rate of an enzyme
reaction with noncompetitive inhibition is equation,

This is the problem 2.21 of the book “Chemical Kinetics and Reaction Dynamics, written by Paul L. Houston”.

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